Benefits of CBD
How is cannabidiol different from marijuana?
CBD stands for cannabidiol. It is the second most prevalent of the active ingredients of cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, which is a cousin of the marijuana plant. While CBD is a component of marijuana (one of hundreds), by itself it does not cause a “high.” According to a report from the World Health Organization, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD.”
The evidence for cannabidiol health benefits
CBD has been touted for a wide variety of health issues, but the strongest scientific evidence is for its effectiveness in treating some of the cruelest childhood epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure medications. In numerous studies, CBD was able to reduce the number of seizures, and in some cases, it was able to stop them altogether. Videos of the effects of CBD on these children and their seizures are readily available on the Internet for viewing, and they are quite striking. Recently the FDA approved the first-ever cannabis-derived medicine for these conditions, Epidiolex, which contains CBD.
CBD is commonly used to address anxiety, and for patients who suffer through the misery of insomnia, studies suggest that CBD may help with both falling asleep and staying asleep.
CBD may offer an option for treating different types of chronic pain. A study from the European Journal of Pain showed, using an animal model, CBD applied on the skin could help lower pain and inflammation due to arthritis. Another study demonstrated the mechanism by which CBD inhibits inflammatory and neuropathic pain, two of the most difficult types of chronic pain to treat. More study in humans is needed in this area to substantiate the claims of CBD proponents about pain control.
Is cannabidiol safe?
Side effects of CBD include nausea, fatigue and irritability. CBD can increase the level in your blood of the blood thinner coumadin, and it can raise levels of certain other medications in your blood by the exact same mechanism that grapefruit juice does. A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So you cannot know for sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other (unknown) elements. We also don’t know the most effective therapeutic dose of CBD for any particular medical condition.
The bottom line on cannabidiol
Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer, which it is not. We need more research but CBD may prove to be an option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies, we can’t pinpoint effective doses, and because CBD is currently is mostly available as an unregulated supplement, it’s difficult to know exactly what you are getting. If you decide to try CBD, talk with your doctor — if for no other reason than to make sure it won’t affect other medications you are taking.
1. Anxiety relief
CBD may be able to help you manage anxiety. Researchers think trusted Source it may change the way your brain’s receptors respond to serotonin, a chemical linked to mental health. Receptors are tiny proteins attached to your cells that receive chemical messages and help your cells respond to different stimuli.
decreasing physiological effects of anxiety, such as an increased heart rate
improving symptoms of post-traumatic stress disorder (PTSD)
inducing sleep in cases of insomnia
CBD has been in the news before, as a possible treatment for epilepsy. Research is still in its early days. Researchers are testing how much CBD is able to reduce the number of seizures in people with epilepsy, as well as how safe it is. The American Epilepsy Society states that cannabidiol research offers hope for seizure disorders, and that research is currently being conducted to better understand safe use.
A study trusted Source from 2016 worked with 214 people with epilepsy. The study participants added oral doses of 2 to 5mg of CBD per day to their existing anti-epilepsy medications. The study’s researchers monitored the participants for 12 weeks, recording any negative side effects and checking on the frequency of their seizures. Overall, participants had 36.5 percent fewer seizures per month. However, severe adverse effects were recorded in 12 percent of the participants.
Researchers are looking at a receptor located in the brain to learn about the ways that CBD could help people with neurodegenerative disorders, which are diseases that cause the brain and nerves to deteriorate over time. This receptor is known as CB1.
Researchers are studying the use of CBD oil for treating:
CBD oil may also reduce the inflammation that can make neurodegenerative symptoms worse. More research is needed to fully understand the effects of CBD oil for neurodegenerative diseases.
4. Pain relief
The effects of CBD oil on your brain’s receptors may also help you manage pain. Studies have shown that cannabis can offer some benefits when taken after chemotherapy treatments. Other pre-clinical studies sponsored by the National Institutes of Health are also looking at the role of cannabis in relieving symptoms caused by:
Nabiximols (Sativex), a multiple sclerosis drug made from a combination of TCH and CBD, is approved in the United Kingdom and Canada to treat MS pain. However, researchers think the CBD in the drug may be contributing more with its anti-inflammatory properties than by acting against the pain. Clinical trials of CBD are necessary to determine whether or not it should be used for pain management.
The effects of CBD on receptors in the immune system may help reduce overall inflammation in the body. In turn, CBD oil may offer benefits for acne management. A human study published in the Journal of Clinical Investigation found that the oil prevented activity in sebaceous glands. These glands are responsible for producing sebum, a natural oily substance that hydrates the skin. Too much sebum, however, can lead to acne.
Before you consider CBD oil for acne treatment, it’s worth discussing with your dermatologist. More human studies are needed to evaluate the potential benefits of CBD for acne.
6. Cancer treatment
Some studies have investigated the role of CBD in preventing cancer cell growth, but research is still in its early stages. The National Cancer InstituteTrusted Source (NCI) says that CBD may help alleviate cancer symptoms and cancer treatment side effects. However, the NCI doesn’t fully endorse any form of cannabis as a cancer treatment. The action of CBD that’s promising for cancer treatment is its ability to moderate inflammation and change how cell reproduce. CBD has the effect of reducing the ability of some types of tumor cells to reproduce.